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Treatment of Idiopathic Parkinsonism

Zandu Zandopa - Product Information


Zandu Zandopa Product Information :

Zandopa is a herbal based supplimentry products for Parkinsons disease.. The Zandopa 200 gm product is a water soluble powder sourced from a plant called ‘Mucuna pruriens’ which contains a natural source of Levadopa. Zandopa is one of the first plant based formulation to have received approval from the United States Food and Drug Administration ( FDA ). HP200 is now sold Worldwide for the treatment of Parkinsons disease under the brand name Zandopa

Zandopa Medicine is a supplimentry product for parkinsonism

  • Zandopa is a readily bioavailable natural source of L-Dopa ( levodopa ).
  • Zandopa has Better Tolerability.
  • Zandopa is suitable for longterm use.
  • Zandopa is economical
  • In parkinson’s disease Zandopa is a natural source of dopamine.

Benefits of Zandopa Medicine :

  • Zandopa, a best supplimentry research product, contains richest natural sources of L-dopa, the plasma half life of which is similar to that from synthetic L-dopa, carbidopa formulations; hence frequency of dosage is comparable.
  • L-dopa of Zandopa is readily bioavailable, crosses BBB more easily than synthetic L-dopa, leading to better efficacy of the product.
  • Zandopa offers predictable efficacy and better tolerance compare to synthetic L-dopa, hence safe for long term use.
  • Zandopa offers better patient compliance due to better toleranceand lesser side effects.

Zandopa Pharmacological Actions :

  • Zandopa replenishes depleted stores of striatal dopamine in Parkinson’s disease.
  • Zandopa improves all the signs and symptoms of Parkinsonism. Bradykinesia responds first followed by rigidity and tremors.
  • Improvement of these primary neurologiacal symptoms is accompanied by similar improvement in overall functional ability.

Zandopa Medicine also favourably influences the psychic behavioural pattern producing a sense of well being and an increased interest in self and surroundings.

Zandopa Safety :

Long term safety studies conducted on laboratory animals have not shown any serious toxicity with Zandopa in a dose as high as 10% of the diet.

Zandopa Indications :

  • Idiopathic Parkinsonism

Zandu Zandopa Precautions :

  • All known precautions and contraindications as applicable to synthetic L-dopa formulations should also be followed while prescribing Zondopa.
  • Monoamine oxidase inhibitors, if taken by patients, must be discontinued atleast 2 weeks prior to institution of Zandopa.
  • As with levodopa, periodic evaluations of hepatic, heamatopoietic, cardiovascular and renal functions are recommended during extended trherapy with Zandopa.
  • Zandopa Medicine should be administered with caution in severe cadiovascular or plumonary disease, brochinal asthma, renal, hepatic or endocrine disease and in presence of peptic ulcer or chronic narrow angle glaucoma.

Zandopa Side Effects :

  • Zandopa Side Effects include nausea, anorexia, cardiac irregularities, orthostatic hypotension, weight gain, hot flushes, numerous dyskinesias and psychiatric symptoms such as agitations, hallucinations, delusions and nightmares.
  • Zandopa Side Effects as encountered with synthetic L-dopa formulations have not been seen to the same severity with Zandopa.

Suggestion for Parkinson’s Disease Patient :

Appropriate treatment helps to keep the patient working and enjoying active life for many years. With proper medication, patience, and perseverance to stay active, your sign and symptoms can be controlled for many years.

Zandopa Dosage :

As directed by the physician.

Directions for use of Zandopa :

  • In a half glass of water ( approx. 100ml ) suspend prescribed dose of Zandopa Powder, stir and drink immediately. 
  • A measure of 7.5gm ( approx. ) is provided in the container.
  • L-dopa content of Zandopa powder is readily soluble in water. 
  • Patients finding difficulty in swallowing of the bulk may be advised to stir the powder in water for nearly one minute. 
  • Clear solution thus obtained may be consumed by the patient.
  • Not to be taken with milk.

Guidelines for Calculation of Zandopa dose :

1.7.5gm powder of Zandopa is standardized to contain approximately 250mg of L-dopa.

2. When switching over from formulations containing L-dopa alone, use the above for calculating equivalent dose of Zandopa i.e patients taking 250mg L-dopa, six times a day will need 7.5gm of Zandopa six times a day.

3. When switching over from formulations containing L-dopa and carbidopa combination calculate the dose of Zandopa as follows:

1 tablet of 100mg L-dopa approx. 

+ 10mg carbidopa or = 2 x 7.5gm

+ 25mg carbidopa of Zandopa

1 tablet of approx

250mg L-dopa = 4 x 7.5gm

+ 250mg carbidopa of Zandopa

4. The plasma " Half Life " of L-dopa, bioavailable from Zandopa is similar to that from synthetic L-dopa or L-dopa / carbidopa formulations. Therefore, the frequency of dosing can be approximately similar.

*  Recent recommendations on the dosage regimen of L-dopa suggest use of smaller dose more frequently than using bigger dose at a lesser frequency for better control of symptoms without encountering the side effects.

*  After initial treatment regimen, the beneficial effects of Zandopa can be maintained for prolonged periods by smaller maintenance dose.

*  Zandopa can be given in combination with synthetic L-dopa preparations.

*  Zandopa replaces only L-dopa hence other associated drugs may be continued.

Zandu Zandopa  - Support for Parkinsons Disease complaints.
Zandopa Treatment of Idiopathic Parkinsonism

Additinoal Information For Zandu Zandopa


Zandopa Composition ( Each 7.5gm contains ) :

 

 

 

 

 

 

 

 

Standardized processed seed powder of Kauncha Mucuna Pruriens 6.525gm in a flavoured base

Brief details about Zandu Company / Brand


Zandu offers a wide range of products from healthcare to lifestyle. In other words, we cure the world naturally with our healing touch. Zandu, for over 100 years has been the leading company of high quality herbal products based on India’s unparallel system of alternative medicine, Ayurveda. Zandu presents a range of ayurvedic healthcare care products that cater to you daily needs and help you live richer and healthier lives. Zandu has a range of natural herbal products spanning over woman and child care, men care, health care and lifestyle. We nurse the world naturally. Zandu works primarily with conventional Ayurvedic products.

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